Deep Moisturizer & Anti-Aging Cream
5% Collagen – 3% Retinol – 5% 4D Hyaluronic Acid
Sigma Essentials Collagen, Retinol & Hyaluronic Acid Cream (Powerful 5-3-5 Formula) Anti-Aging Moisturizer for Face, Neck & Décolleté – Professional-Grade Daily Moisturizer Face Cream with 4 Different Molecular Weights of Hyaluronic Acid, Each Penetrating Different Skin Layers for Superior Hydration – Premium Hydrolyzed Marine Collagen for Skin Firming – Two Value Sizes: 1.85 oz (55 ml) and Jumbo 3.7 oz (110 ml) – 3 Years Shelf Life – Touchless 1 Finger Cream Dispenser




Regular Price $47.80
3% Retinol Serum: Your Next-Level Professional Formula
Designed for maximum age-defying results, this professional-strength 3% Retinol formula offers deep skin renewal.
Graduated Introduction is Key
Begin by applying a pea-sized amount once weekly at night. Gradually increase frequency only as your skin demonstrates tolerance.
Important Guidelines for ALL Users:
✓ HIGH POTENCY: This is a maximum-strength 3% Retinol. While some users acclimate quickly, we strongly recommend that first-time Retinol users begin with a lower concentration (0.5% – 1.0%) for a minimum of six weeks before advancing to this formula.
✓ BEGINNER EXCEPTION: If you are a committed beginner choosing to start with this 3% formula, you must perform a patch test and strictly adhere to the graduated introduction schedule. Instructions further down this page listed under the heading “How to Use Your Professional-Grade Anti-Aging Cream for Maximum Results”
✓ Do Not Use If: You have highly sensitive skin or are pregnant or breastfeeding.
✓ Sun Safety is Non-Negotiable: Apply a broad-spectrum sunscreen SPF 30+ daily. Increased photosensitivity lasts up to 7 days after last use.
✓ Monitor Your Skin: If you experience excessive or prolonged redness, peeling, or irritation, reduce your application frequency immediately.
Multi-Molecular Hyaluronic Acid vs Standard Hyaluronic Acid
Discover Advanced 4D Hyaluronic Acid Age-Defying Serum for Deep Hydration
Transform your skincare with our breakthrough multi-molecular hyaluronic acid formula featuring potent retinol and marine collagen. Our innovative 5-3-5 complex combines four distinct molecular weights targeting multiple skin layers, creating advanced moisture retention for comprehensive hydration and wrinkle reduction.
Unlike luxury anti-aging creams with premium pricing, Sigma Essentials offers sophisticated triple-ingredient formulas at direct-to-consumer value. Our concentrated formula delivers powerful age-defying results for experienced users, targeting fine lines, wrinkles, uneven tone, and elasticity loss.
Experience Visible Age-Defying Results with Deep-Penetrating Formula:
✓ Advanced wrinkle reduction through potent 3% retinol
✓ Enhanced skin firmness with 5% premium marine collagen
✓ Superior hydration and plumping via 5% 4D hyaluronic acid
✓ Diminished appearance of uneven tone and age spots
✓ Long-lasting moisture retention for mature skin needs
✓ Improved skin texture, radiance, and overall complexion
This versatile age-defying facial cream works seamlessly as standalone formula or combined with existing skincare. The rich yet lightweight formula absorbs efficiently, delivering intensive hydration and age-defying actives where skin needs them most. Our advanced concentration provides immediate plumping effects and cumulative long-term benefits for sustained skin renewal and wrinkle prevention.
Each premium bottle contains expertly-tested advanced ingredients suitable for sensitive skin and all types.
Join our growing community discovering transformative multi-molecular hyaluronic acid with retinol and collagen. Revitalize complexion with effective age-defying cream for mature skin at competitive prices today.



Why Marine Collagen Outperforms Traditional Collagen sources?
Superior Absorption Through Advanced Molecular Structure
Premium marine-sourced collagen peptides feature uniquely small molecular structures that revolutionize how your skin processes this essential anti-aging protein. Unlike traditional bovine or porcine collagen sources, our premium-grade fish collagen peptides offer maximum bioavailability and 90% superior absorption rates, allowing your skin to absorb and utilize this powerful wrinkle-fighting protein more effectively for visible skin rejuvenation and anti-aging results.
Eco-Conscious Beauty Choice
Our sustainably sourced marine collagen comes from carefully selected wild-caught fish skin and scales, transforming natural fishing industry by-products into powerful anti-aging beauty ingredients. This environmentally responsible clean beauty sourcing process ensures you can maintain your premium skincare routine while supporting ocean sustainability and eco-friendly anti-aging practices.
Pure Type 1 Collagen for Maximum Skin Benefits
Premium marine collagen delivers concentrated Type 1 collagen, the identical primary collagen found naturally in human skin, hair, and nails. This perfect biological match between marine collagen peptides and your body’s own collagen structure promotes optimal skin elasticity and enhanced skin firmness for comprehensive anti-aging transformation.
Hypoallergenic Marine Collagen for Sensitive Skin Types
Premium marine collagen minimizes allergic reactions compared to bovine or porcine sources, making it ideal anti-aging skincare for those with land animal protein allergies, sensitive skin concerns, and reactive skin types. Our gentle marine collagen formula is expertly-tested and suitable for all skin types including sensitive and mature skin.
Overall, premium marine collagen excels for discerning women seeking enhanced skin elasticity, stronger hair, resilient nails, and visible age-defying benefits through superior bioavailability, sustainable sourcing, and optimal molecular structure for luxury skincare transformation at competitive prices.



Key Benefits of Premium Marine Collagen for Anti-Aging:
Enhanced skin elasticity and deep hydration for wrinkle reduction
✓ Reduced appearance of fine lines and age-related wrinkles
✓ Strengthened hair follicles and nail health
✓ Superior absorption rate and bioavailability (90% higher)
✓ Sustainable clean beauty solution
✓ Pure Type 1 collagen source for skin matching
✓ Ocean-friendly eco-conscious skincare choice
Experience the transformative difference that premium marine collagen can make in your daily anti-aging skincare routine.
Support both your beauty goals and environmental consciousness with nature’s most bioavailable collagen source for professional-grade skincare results at affordable luxury prices.
Experience the transformative difference that premium marine collagen can make in your daily anti-aging skincare routine. Support both your beauty goals and environmental consciousness with nature’s most bioavailable collagen source for professional-grade wrinkle reduction and skin firming results at competitive prices

Why Choose Sigma Essentials
Premium Excellence in Every Age-Defying Detail
Our commitment to luxury skincare quality begins with carefully selected, premium ingredients sourced globally from trusted suppliers. Each advanced anti-aging formulation is developed by skincare experts, PhD cosmetic scientists, and specialists, combining cutting-edge innovation with proven age-defying actives for superior wrinkle reduction at competitive prices.
Superior Standards for Luxury Skincare:
• Premium ingredients with optimal concentrations for maximum efficacy • Advanced manufacturing in world-class certified facilities • Rigorous testing protocols and safety validation • Expert formulations by PhD chemists and skincare authorities • Sustainable packaging with innovative touchless dispensing
The Sigma Essentials Difference: Affordable Luxury
Unlike mass drugstore skincare, our advanced age-defying cream delivers:
✓ Precise 5-3-5 formula (5% Marine Collagen, 3% Retinol, 5% 4D Hyaluronic Acid)
✓ Advanced 4D Multi-Molecular Hyaluronic Acid for deep penetration
✓ Premium Type-1 Marine Collagen for visible firming
✓ Touchless dispensing for hygiene and preservation
✓ Direct pricing for luxury without retail markup


How to Use Your Professional-Grade Anti-Aging Cream for Maximum Results
Application Instructions for Professional-Strength Skincare:
Apply a small amount of our 5-3-5 formula anti-aging cream to clean, dry skin on face, neck, and décolleté. Gently massage the professional-grade moisturizer until completely absorbed for optimal penetration of active ingredients.
Usage for New/Sensitive Skin:
Start with a pea size amount just once per week at night for the first 2-3 weeks. Gradually increase frequency as your skin adapts to this potent formula. Once full tolerance builds, use daily for best results.
⚠️ IMPORTANT SUN PROTECTION:
SPF 30+ Sunscreen REQUIRED: This 3% retinol increases sun sensitivity. Always apply broad-spectrum sunscreen daily.
IMPORTANT: PATCH TEST REQUIRED for Safe Skincare Use
Apply a small amount of our hypoallergenic anti-aging cream to inner forearm and wait 24 hours before facial application. Discontinue use immediately if skin irritation, redness, or allergic reactions occur. Individual skin sensitivities may vary with premium grade ingredients.

Consult your dermatologist or healthcare professional before use if you have sensitive skin, known allergies, or existing skin conditions. This potent formula contains active ingredients that may cause initial skin adjustment.
For external skincare use only. Avoid direct eye contact. Keep out of reach of children. Store in cool, dry place to maintain product efficacy.
What Are People Saying About Our Clinical-Strength Anti-Aging Cream?
Experience the Transformative Anti-Aging Results – Clinical Testing & Early Customer 4.5 stars Feedback
Discover why early adopters and beta testers are choosing Sigma Essentials USA for professional-grade skincare results at affordable luxury prices. Our clinically tested 5-3-5 formula delivers proven anti-aging transformation in independent laboratory studies:
🌟 94% of clinical study participants reported instant hydration and visible plumping of their skin with superior moisture retention using our 4D hyaluronic acid anti-aging cream
🌟 92% of beta testers felt their mature skin was deeply nourished and completely rejuvenated after using our marine collagen retinol formula
🌟 92% of early users noticed significant improvement in skin suppleness and moisture replenishment with our professional-grade anti-aging moisturizer
🌟 95% of clinical trial participants saw noticeable smoothing of fine lines and skin texture improvement with our revolutionary 4D hyaluronic acid face cream for wrinkle reduction
Join women discovering our expert-founded skincare. Experience advanced age-defying results with premium ingredients at direct prices.
Ready to try our breakthrough formula? See why women choose Sigma Essentials for luxury anti-aging without luxury prices.

Can I Use All 3 Anti-Aging Ingredients at the Same Time?
Safe Use of Marine Collagen, Retinol, and Hyaluronic Acid for Maximum Age-Defying Results
Yes, you can safely combine marine collagen, advanced retinol, and 4D hyaluronic acid in our premium skincare formulations, including age-defying serums, moisturizing creams, and collagen supplements. Our expertly formulated 5-3-5 combination delivers synergistic age-defying benefits for comprehensive wrinkle reduction and skin renewal.
Why This Triple-Action Anti-Aging Combination Works:
✓ Marine Collagen (5%) – Provides structural support and skin firming for enhanced elasticity
✓ Premium Retinol (3%) – Accelerates cellular turnover and collagen production for wrinkle reduction
✓ 4D Hyaluronic Acid (5%) – Delivers deep hydration and plumps fine lines for smoother skin texture
Our premium-grade formula is specifically designed by cosmetic scientists to ensure ingredient compatibility and maximum bioavailability. Each active ingredient enhances the others’ effectiveness, creating powerful age-defying synergy that delivers luxury skincare results at affordable prices.
Expert-tested and suitable for most skin types, this triple-ingredient approach represents the gold standard in advanced age-defying skincare formulation.
Conclusion
When used together as directed, collagen, retinol, and hyaluronic acid form a potent skincare combination
This trio works synergistically to promote firmer, smoother, and more youthful-looking skin, while also laying the groundwork for healthy aging.