13% Actives. Clinical Retinol Results.
- 5% Collagen • 3% Retinol • 5% 4D Hyaluronic Acid
✓ $6.46/oz (lowest price per ounce)
✓ 13% disclosed actives (3% Retinol, 5% Collagen, 5% 4D HA)
✓ 100% transparency (no proprietary blends)
Sale ends soon • Fresh stock • 4.7 stars ★ on Amazon
13% Active Ingredients—More Than Any Competitor. See the Proof ↓
Full ingredient transparency • Premium quality • Lower cost per ounce
↓ Scroll down to compare actives, ratings & price/oz
🔥 CYBER MONDAY PRICE CHECK (Updated Nov 29, 2025)
Even with competitors’ CYBER MONDAY discounts, Sigma Essentials delivers:
✅ $6.46/oz (lowest price per ounce)
✅ 13% disclosed actives (competitors disclose 0–9%)
✅ 100% transparency (no proprietary blends)
No gimmicks. Better quality. Better price.
Regular Price $47.80
3% Retinol Cream: Your Next-Level Professional Formula
See visible age‑defying results with 3% Retinol, 5% Collagen, and 5% 4D Hyaluronic Acid. Deep hydration, improved firmness, smoother texture—at the lowest cost per ounce.
IMPORTANT GUIDELINES
- High potency: 3% Retinol. New users start with 0.5–1.0% for 6+ weeks.
- Beginners: Patch test; follow the graduated schedule below.
- Do not use if: Highly sensitive skin, pregnant, or breastfeeding.
- Sun safety: SPF 30+ daily; sensitivity up to 7 days after last use.
- Monitor your skin: If redness/peeling persists, reduce frequency.
- We disclose exact percentages and safe‑use steps—so you know exactly what you’re getting.
Professional‑strength formula: 3% Retinol • 5% Collagen • 5% 4D Hyaluronic Acid
Exact percentages disclosed—compare ingredients, price per ounce, and transparency below
Using one of these? See how they compare—actives, price, and full transparency
Sigma Essentials vs. 5 Leading Anti-Aging Creams - Scroll right to compare brands → | Scroll down for actives %, ingredients & price ↓
Compare Actives, Ratings & Price Per Oz
Lower upfront cost ($23.90 vs. $29.72 simplyvital), bigger bottle (3.7 oz vs. 3.4 oz), and full active transparency (13% disclosed vs. proprietary blends)
Swipe → to compare on mobile
Sigma Essentials 3.7 oz (110 ml)
SimplyVital 3.4 oz (100 ml)
SimplyVital 1.7 oz (50 ml)
Enaskin 1.7 oz (50 ml)
Maree 1.7 oz (50 ml)
Remedial Pax 1,85 oz (55 ml)
Key takeaway: Sigma Essentials offers 13% disclosed actives at $6.46/oz — the highest actives at the lowest price per ounce in this comparison.
✓ More product (3.7 oz vs 3.0 oz average)
✓ Lower cost per oz ($6.46 vs $7.99+ average)
✓ 13% disclosed actives vs 0–9% competitors
✓ 100% transparency (no proprietary blends)
** 4D Hyaluronic Acid (Multi-Molecular Weight HA): Contains 4 different molecular weights of Hyaluronic Acid for multi-layer skin penetration. Low-MW HA penetrates deeply to plump from within; high-MW HA forms a moisture barrier on the surface. Standard HA (used by Simply Vital and MAREE) typically contains only 1–2 molecular weights, limiting penetration and hydration depth. Both Sigma Essentials and ENASKI use 4D HA and disclose this in their Amazon listings.
Disclaimer: ASIN numbers, prices, and ingredient information have been carefully collected from publicly available Amazon product listings as of November 29, 2025. All data is subject to change as manufacturers may update formulations, pricing, or product specifications at any time. Most brands offer 10–15% discounts with subscriptions. Sigma Essentials gives you the lowest price upfront—no subscription required.
While we strive for accuracy in all comparisons, mistakes can happen and are unintentional. It is not our intention to misrepresent any facts or competitor products. We are confident in the superior value and transparency of Sigma Essentials. If you notice any inaccuracies in this comparison, please contact us immediately using the Contact form above so we can correct the information promptly.
We recommend verifying current prices, formulations, and availability directly on Amazon or the manufacturer’s website before making a purchase decision.
🧪 Understanding PPM (Parts Per Million) vs. Percentage
Some brands use PPM (parts per million) instead of percentages. PPM numbers can look large, but the actual concentration may be very small.
Here’s what those numbers really mean:
Conversion Guide
1% = 10,000 ppm / 0.1% = 1,000 ppm / 0.01% = 100 ppm
✨The Sigma Essentials Advantage & Overall Better Value for great results.
100% satisfaction or your money back
✅ Highest customer rating: 4.7 stars on Amazon
✅ Lowest price without subscription required
✅ Best price per ounce: $6.46/oz (up to 54% less than competitors)
✅ Largest size available: 3.7 oz (more product, better value)
✅ Full transparency: 3% Retinol, 5% Collagen, 5% 4D HA all disclosed (most brands only disclose retinol %)
✅ Highest disclosed active content: ~18% total actives (13% key actives: Retinol, Collagen, 4D HA + botanical actives)
✅ One of 2 brands that include 4D Hyaluronic Acid for multi-layer deep hydration
✅ Highest-Strength Formula for less: Same powerful 3% retinol strength as leading sellers but provides over 26% savings per ounce – plus fully disclosed Collagen and 4D Hyaluronic Acid.
Multi-Molecular Hyaluronic Acid vs. regular Hyaluronic Acid
Discover Advanced 4D Hyaluronic Acid Age-Defying Serum for Deep Hydration
Transform your skincare with our breakthrough multi-molecular hyaluronic acid formula featuring potent retinol and marine collagen. Our innovative 5-3-5 complex combines four distinct molecular weights targeting multiple skin layers, creating advanced moisture retention for comprehensive hydration and wrinkle reduction.
Unlike luxury anti-aging creams with premium pricing, Sigma Essentials offers sophisticated triple-ingredient formulas at direct-to-consumer value. Our concentrated formula delivers powerful age-defying results for experienced users, targeting fine lines, wrinkles, uneven tone, and elasticity loss.
Experience Visible Age-Defying Results with Deep-Penetrating Formula:
✓ Advanced wrinkle reduction through potent 3% retinol
✓ Enhanced skin firmness with 5% premium marine collagen
✓ Superior hydration and plumping via 5% 4D hyaluronic acid
✓ Diminished appearance of uneven tone and age spots
✓ Long-lasting moisture retention for mature skin needs
✓ Improved skin texture, radiance, and overall complexion
This versatile age-defying facial cream works seamlessly as standalone formula or combined with existing skincare. The rich yet lightweight formula absorbs efficiently, delivering intensive hydration and age-defying actives where skin needs them most. Our advanced concentration provides immediate plumping effects and cumulative long-term benefits for sustained skin renewal and wrinkle prevention.
Each premium bottle contains expertly-tested advanced ingredients suitable for sensitive skin and all types.
Join our growing community discovering transformative multi-molecular hyaluronic acid with retinol and collagen. Revitalize complexion with effective age-defying cream for mature skin at competitive prices today.
Why Marine Collagen Outperforms Traditional Collagen sources?
Superior Absorption Through Advanced Molecular Structure
Premium marine-sourced collagen peptides feature uniquely small molecular structures that revolutionize how your skin processes this essential anti-aging protein. Unlike traditional bovine or porcine collagen sources, our premium-grade fish collagen peptides offer maximum bioavailability and 90% superior absorption rates, allowing your skin to absorb and utilize this powerful wrinkle-fighting protein more effectively for visible skin rejuvenation and anti-aging results.
Eco-Conscious Beauty Choice
Our sustainably sourced marine collagen comes from carefully selected wild-caught fish skin and scales, transforming natural fishing industry by-products into powerful anti-aging beauty ingredients. This environmentally responsible clean beauty sourcing process ensures you can maintain your premium skincare routine while supporting ocean sustainability and eco-friendly anti-aging practices.
Pure Type 1 Collagen for Maximum Skin Benefits
Premium marine collagen delivers concentrated Type 1 collagen, the identical primary collagen found naturally in human skin, hair, and nails. This perfect biological match between marine collagen peptides and your body’s own collagen structure promotes optimal skin elasticity and enhanced skin firmness for comprehensive anti-aging transformation.
Hypoallergenic Marine Collagen for Sensitive Skin Types
Premium marine collagen minimizes allergic reactions compared to bovine or porcine sources, making it ideal anti-aging skincare for those with land animal protein allergies, sensitive skin concerns, and reactive skin types. Our gentle marine collagen formula is expertly-tested and suitable for all skin types including sensitive and mature skin.
Overall, premium marine collagen excels for discerning women seeking enhanced skin elasticity, stronger hair, resilient nails, and visible age-defying benefits through superior bioavailability, sustainable sourcing, and optimal molecular structure for luxury skincare transformation at competitive prices.
Key Benefits of Premium Marine Collagen for Anti-Aging:
Enhanced skin elasticity and deep hydration for wrinkle reduction
✓ Reduced appearance of fine lines and age-related wrinkles
✓ Strengthened hair follicles and nail health
✓ Superior absorption rate and bioavailability (90% higher)
✓ Sustainable clean beauty solution
✓ Pure Type 1 collagen source for skin matching
✓ Ocean-friendly eco-conscious skincare choice
Experience the transformative difference that premium marine collagen can make in your daily anti-aging skincare routine.
Support both your beauty goals and environmental consciousness with nature’s most bioavailable collagen source for professional-grade skincare results at affordable luxury prices.
Experience the transformative difference that premium marine collagen can make in your daily anti-aging skincare routine. Support both your beauty goals and environmental consciousness with nature’s most bioavailable collagen source for professional-grade wrinkle reduction and skin firming results at competitive prices
Why Choose Sigma Essentials
Premium Excellence in Every Age-Defying Detail
Our commitment to luxury skincare quality begins with carefully selected, premium ingredients sourced globally from trusted suppliers. Each advanced anti-aging formulation is developed by skincare experts, PhD cosmetic scientists, and specialists, combining cutting-edge innovation with proven age-defying actives for superior wrinkle reduction at competitive prices.
Superior Standards for Luxury Skincare:
• Premium ingredients with optimal concentrations for maximum efficacy • Advanced manufacturing in world-class certified facilities • Rigorous testing protocols and safety validation • Expert formulations by PhD chemists and skincare authorities • Sustainable packaging with innovative touchless dispensing
The Sigma Essentials Difference: Affordable Luxury
Unlike mass drugstore skincare, our advanced age-defying cream delivers:
✓ Precise 5-3-5 formula (5% Marine Collagen, 3% Retinol, 5% 4D Hyaluronic Acid)
✓ Advanced 4D Multi-Molecular Hyaluronic Acid for deep penetration
✓ Premium Type-1 Marine Collagen for visible firming
✓ Touchless dispensing for hygiene and preservation
✓ Direct pricing for luxury without retail markup
How to Use Your Professional-Grade Anti-Aging Cream for Maximum Results
Application Instructions for Professional-Strength Skincare:
Apply a small amount of our 5-3-5 formula anti-aging cream to clean, dry skin on face, neck, and décolleté. Gently massage the professional-grade moisturizer until completely absorbed for optimal penetration of active ingredients.
Usage for New/Sensitive Skin:
Start with a pea size amount just once per week at night for the first 2-3 weeks. Gradually increase frequency as your skin adapts to this potent formula. Once full tolerance builds, use daily for best results.
⚠️ IMPORTANT SUN PROTECTION:
SPF 30+ Sunscreen REQUIRED: This 3% retinol increases sun sensitivity. Always apply broad-spectrum sunscreen daily.
IMPORTANT: PATCH TEST REQUIRED for Safe Skincare Use
Apply a small amount of our hypoallergenic anti-aging cream to inner forearm and wait 24 hours before facial application. Discontinue use immediately if skin irritation, redness, or allergic reactions occur. Individual skin sensitivities may vary with premium grade ingredients.
Consult your dermatologist or healthcare professional before use if you have sensitive skin, known allergies, or existing skin conditions. This potent formula contains active ingredients that may cause initial skin adjustment.
For external skincare use only. Avoid direct eye contact. Keep out of reach of children. Store in cool, dry place to maintain product efficacy.
What Are People Saying About Our Clinical-Strength Anti-Aging Cream?
Experience the Transformative Anti-Aging Results – Clinical Testing & Early Customer 4.5 stars Feedback
Discover why early adopters and beta testers are choosing Sigma Essentials USA for professional-grade skincare results at affordable luxury prices. Our clinically tested 5-3-5 formula delivers proven anti-aging transformation in independent laboratory studies:
🌟 94% of clinical study participants reported instant hydration and visible plumping of their skin with superior moisture retention using our 4D hyaluronic acid anti-aging cream
🌟 92% of beta testers felt their mature skin was deeply nourished and completely rejuvenated after using our marine collagen retinol formula
🌟 92% of early users noticed significant improvement in skin suppleness and moisture replenishment with our professional-grade anti-aging moisturizer
🌟 95% of clinical trial participants saw noticeable smoothing of fine lines and skin texture improvement with our revolutionary 4D hyaluronic acid face cream for wrinkle reduction
Join women discovering our expert-founded skincare. Experience advanced age-defying results with premium ingredients at direct prices.
Ready to try our breakthrough formula? See why women choose Sigma Essentials for luxury anti-aging without luxury prices.
Can I Use All 3 Anti-Aging Ingredients at the Same Time?
Safe Use of Marine Collagen, Retinol, and Hyaluronic Acid for Maximum Age-Defying Results
Yes, you can safely combine marine collagen, advanced retinol, and 4D hyaluronic acid in our premium skincare formulations, including age-defying serums, moisturizing creams, and collagen supplements. Our expertly formulated 5-3-5 combination delivers synergistic age-defying benefits for comprehensive wrinkle reduction and skin renewal.
Why This Triple-Action Anti-Aging Combination Works:
✓ Marine Collagen (5%) – Provides structural support and skin firming for enhanced elasticity
✓ Premium Retinol (3%) – Accelerates cellular turnover and collagen production for wrinkle reduction
✓ 4D Hyaluronic Acid (5%) – Delivers deep hydration and plumps fine lines for smoother skin texture
Our premium-grade formula is specifically designed by cosmetic scientists to ensure ingredient compatibility and maximum bioavailability. Each active ingredient enhances the others’ effectiveness, creating powerful age-defying synergy that delivers luxury skincare results at affordable prices.
Expert-tested and suitable for most skin types, this triple-ingredient approach represents the gold standard in advanced age-defying skincare formulation.
Conclusion
When used together as directed, collagen, retinol, and hyaluronic acid form a potent skincare combination
This trio works synergistically to promote firmer, smoother, and more youthful-looking skin, while also laying the groundwork for healthy aging.